Biguanide drug-containing jelly preparation

Details Biguanide drug-containing jelly preparation Biguanide drug-containing jelly preparation

A - Human Necessities

61

K

A61K 31/155 (2006.01) A61K 9/06 (2006.01) A61K 47/04 (2006.01) A61K 47/20 (2006.01) A61K 47/36 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2542755

A jelly preparation containing biguanide medicine that at administration, suppresses bitterness and harsh taste and reduces discomfort, and that despite having stability, excels in medicine release in the gastrointestinal tract. There is provided a jelly preparation containing biguanide medicine characterized in that a biguanide medicine, an inorganic acid and a water soluble polymer are contained. By virtue of the particular action of the inorganic acid, the conflicting properties of excelling in jelly preparation stability and medicine release can be simultaneously realized.

L'invention concerne une préparation à base de gelée qui contient un médicament de biguanide. Son administration supprime l'amertume et la dureté de goût et réduit l'inconfort. En dépit de la stabilité intrinsèque du produit, celui-ci a un excellent potentiel de libération dans le tube digestif. On décrit une préparation de gelée renfermant un médicament de biguanide, ainsi qu'un acide inorganique et un polymère hydrosoluble. L'effet particulier de l'acide inorganique fait que l'on peut réunir les propriétés contraires d'une excellente stabilité de préparation à base de gelée et d'une libération de médicament.

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