C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 9/00 (2006.01) A61K 31/56 (2006.01) C07J 41/00 (2006.01)
Patent
CA 2642220
The present invention relates to compounds of formula (I) wherein: Ri is hydrogen or an alkyl group; R2 is hydrogen or a halogen, nitro, alkyloxy, amino or carboxy group; Y is CH2, oxygen or sulfur; n is an integer from 1 to 4, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof for the treatment of FXR-mediated diseases or conditions.
La présente invention concerne des composés de formule (I) dans lesquels : Ri est de l'hydrogène ou un groupement alkyle ; R2 est de l'hydrogène ou un groupement halogène, nitro, alkyloxy, amino ou carboxy ; Y est CH2, de l'oxygène ou du soufre ; n est un nombre entier de 1 à 4, et des sels pharmaceutiquement acceptables, des solvates ou des conjugués d'acides aminés de ceux-ci pour le traitement de maladies ou d'états induits par FXR.
Fiorucci Stefano
Pellicciari Roberto
Pruzanski Mark
Bennett Jones Llp
Fiorucci Stefano
Intercept Pharmaceuticals Inc.
Pellicciari Roberto
Pruzanski Mark
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