Bile acid derivatives, processes for the preparation thereof...

Details Bile acid derivatives, processes for the preparation thereof... Bile acid derivatives, processes for the preparation thereof...

C - Chemistry, Metallurgy

07

J

167/195, 260/62

C07J 9/00 (2006.01) A61K 31/575 (2006.01)

Patent

CA 2014544

Compounds of general formula I (See formula I) wherein R1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carboanions the corresponding derivatives Which have previously been protected, and subsequently deprotecting and decarboxylating them.

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