Bilirubin-resistant determination of uric acid

Details Bilirubin-resistant determination of uric acid Bilirubin-resistant determination of uric acid

G - Physics

01

N

150/3, 150/9

G01N 33/48 (2006.01) C12Q 1/60 (2006.01) C12Q 1/62 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1134247

ABSTRACT OF THE DISCLOSURE A composition, test device, method of making a test device and process for bilirubin-resistant determination or uric acid in a fluid sample are disclosed. More particularly, the composition is of the type comprising means responsive to the presence of uric acid in the sample, a phenol and 4- aminophenazone to which resistance to interference by bilirubin is imparted by inclusion therein of reagent means comprising a ferrocyanide ion. The uric acid responsive means is preferably of the type which determines peroxides formed from enzymatic conversion of uric acid. The compo- sition can optionally be incorporated with a carrier to provide a test device.

329191

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