Bilirubin-resistant determination of uric acid and cholesterol

Details Bilirubin-resistant determination of uric acid and cholesterol Bilirubin-resistant determination of uric acid and cholesterol

G - Physics

01

N

150/11, 150/14

G01N 33/52 (2006.01) C12Q 1/60 (2006.01) C12Q 1/62 (2006.01) G01N 33/92 (2006.01)

Patent

CA 1144050

ABSTRACT OF THE DISCLOSURE A composition, test device, method of making a test device and process for bilirubin-resistant determination of an analyte selected from uric acid or cholesterol in a fluid sample are disclosed. More particularly, the composition is of the type comprising means responsive to the presence of the particular analyte to be determined in the sample, a phenol and 4-aminophenazone to which resistance to inter- ference by bilirubin is imparted by inclustion therein of reagent means comprising a ferrocyanide ion. The uric acid or cholesterol responsive means is preferably of the type which determines peroxides formed from enzymatic conversion of the analyte. The composition can optionally be incor- porated with a carrier to provide a test device.

369625

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