Bin1 as a prognostic marker in cardiovascular disease

Details Bin1 as a prognostic marker in cardiovascular disease Bin1 as a prognostic marker in cardiovascular disease

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/12 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2759698

The present disclosure provides methods involving use of BIN1 expression levels, in heart tissue, in evaluating the risk of cardiac mortality in a patient diagnosed with congestive heart failure. The methods finds use in evaluating patients who are heart transplant candidates, as well as in assessing efficacy of treatment in congestive heart failure patients.

La présente invention se rapporte à des procédés impliquant l'utilisation de niveaux d'expression de BIN1 dans des tissus cardiaques pour évaluer le risque de mortalité cardiaque d'un patient diagnostiqué comme présentant une insuffisance cardiaque congestive. Les procédés trouvent leur utilisation dans l'évaluation des patients candidats à une transplantation cardiaque ainsi que dans l'évaluation de l'efficacité du traitement des patients présentant une insuffisance cardiaque congestive.

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