C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 1/10 (2006.01) C07K 14/705 (2006.01) G01N 33/48 (2006.01)
Patent
CA 2647271
The invention relates to a polypeptide dimer, wherein both protomers have a sequence according to SEQ ID NO: 1, wherein at least one phosphocholine derivative is attached to said polypeptide. Said polypeptide shows a specific binding for C-reactive protein (CRP). The invention further relates to use of the polypeptide in assays for determineing the concentration of CRP, purification of CRP and compositions comprising CRP.
La présente invention concerne un dimère de polypeptide dans lequel les deux protomères présentent une séquence SEQ ID NO: 1, au moins un dérivé de phosphocholine étant relié audit polypeptide. Le polypeptide présente une liaison spécifique pour la protéine C-réactive (CRP). Cette invention concerne également l'utilisation dudit polypeptide dans le cadre de dosages pour déterminer la concentration en CRP, ainsi qu'un procédé de purification de CRP et des compositions comprenant CRP.
Modpro Ab
Smart & Biggar
LandOfFree
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