Binding member for gm-csf receptor

Details Binding member for gm-csf receptor Binding member for gm-csf receptor

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2647449

Binding members for alpha chain of receptor for granulocyte macrophage colony stimulating factor (GM-CSFR ), especially antibody molecules. Use of the binding members in treating inflammatory and autoimmune diseases, e.g. rheumatoid arthritis, asthma, allergic response, multiple sclerosis, myeloid leukaemia and atherosclerosis.

L'invention concerne des éléments de liaison à la chaîne alpha du récepteur de facteur stimulant le développement des colonies de granulocytes et macrophages (GM-CSFR.alpha.), en particulier des molécules d'anticorps, ainsi que l'utilisation de ces éléments de liaison dans le traitement de maladies inflammatoires et auto-immunes, par exemple la polyarthrite rhumatoïde, l'asthme, la réponse allergique, la sclérose en plaques, la leucémie myéloïde et l'athérosclérose.

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