Binding members for interleukin-4 receptor alpha (il-4ra) - 173

Details Binding members for interleukin-4 receptor alpha (il-4ra) - 173 Binding members for interleukin-4 receptor alpha (il-4ra) - 173

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) C12N 15/13 (2006.01) C07K 14/715 (2006.01)

Patent

CA 2708871

Binding members, especially antibody molecule s, for interleukin (IL)-4 receptor alpha (IL- 4R ), and their therapeutic use e.g. in treating or preventing diso rders associated with IL-4R, IL-4 and/or IL-13, examples of which are asthma and COPD.

La présente invention concerne des éléments de liaison, particulièrement des molécules d'anticorps, pour le récepteur alpha de l'interleukine -4 (IL- 4R), et leur utilisation thérapeutique, par exemple, dans le traitement ou la prévention de troubles associés à l'IL-4R, l'IL-4 et/ou l'IL-13, tels que l'asthme et la broncho-pneumopathie chronique obstructive.

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