Binding moieties based on shark ignar domains

Details Binding moieties based on shark ignar domains Binding moieties based on shark ignar domains

C - Chemistry, Metallurgy

07

K

C07K 14/46 (2006.01) A61K 38/17 (2006.01) A61P 43/00 (2006.01) C07H 21/04 (2006.01) C12N 15/85 (2006.01) G01N 33/68 (2006.01) G06F 17/14 (2006.01)

Patent

CA 2567655

The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.

La présente invention a trait à de nouveaux récepteurs d'antigène d'immunoglobuline (IgNAR) dérivés de poissons et leurs utilisations. En particulier, l'invention a trait à des domaines variables d'IgNAR modifiés et à des domaines dérivés des membres de la superfamille des immunoglobulines qui ont été modifiés pour inclure des éléments structurels dérivés des domaines variables d'IgNAR.

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