C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/10 (2006.01) A61K 39/395 (2006.01) A61P 31/14 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2568162
The present invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the postexposure prophylaxis of rabies.
La présente invention concerne des molécules de liaison spécifique au virus de la rage pouvant neutraliser le virus. L'invention concerne égalemennt des molécules d'acides nucléiques codant pour les molécules de liaison, des compositions contenant les molécules de liaison, et des méthodes d'identification ou de production des molécules de liaison. Les molécules de liaison peuvent être utilisées dans le diagnostic, la prophylaxie et/ou le traitement d'un état généré par le virus de la rage. Lesdites molécules peuvent être utilisées, de préférence, dans la prophylaxie de post-exposition à la rage.
Bakker Alexander Berthold Hendrik
de Kruif Cornelis Adriaan
Kramer Robert Arjen
Marissen Willem Egbert
Borden Ladner Gervais Llp
Crucell Holland B.v.
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