C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 31/7088 (2006.01) A61K 38/21 (2006.01) A61K 39/42 (2006.01) A61P 31/14 (2006.01) C07K 16/10 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) C40B 30/04 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2591665
The present invention provides human binding molecules specifically binding to West Nile virus and having West Nile virus neutralizing activity, nucleic acid molecules encoding the human binding molecules, compositions comprising the human binding molecules and methods of identifying or producing the human binding molecules. The human binding molecules can be used in the diagnosis, post-exposure prophylaxis and/or treatment of a condition resulting from West Nile virus.
La présente invention concerne des molécules de liaison humaines se liant spécifiquement au virus du Nil Occidental, et présentant une activité neutralisante pour le virus du Nil Occidental. L'invention concerne également des molécules d'acide nucléique codant ces molécules, des compositions les comprenant, et des procédés permettant de les identifier ou de les produire. Ces molécules conviennent au diagnostic, à la prophylaxie après exposition et/ou au traitement d'un état imputable au virus du Nil Occidental.
de Kruif Cornelis Adriaan
Throsby Mark
Borden Ladner Gervais Llp
Crucell Holland B.v.
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