C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/04 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 7/64 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2354599
Methods for detecting human factor VIII or factor VIII-like polypeptides in and isolating it from solutions such as blood or conditioned media are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human factor VIII and/or a factor VIII-like polypeptide and form a binding complex therewith. Preferred polypeptide binding moieties are particularly disclosed.
L'invention concerne des procédés permettant de détecter le facteur VIII humain ou des polypeptides de type facteur VIII dans des solutions telles que le sang ou un milieu conditionné et de les isoler dans ces solutions. L'invention concerne également des réactifs convenant pour ces procédés et comprenant des portions de liaison capables de reconnaître le facteur VIII humain et/ou un polypeptide de type facteur VIII et de former un complexe de liaison avec celui-ci. L'invention concerne en particulier des portions de liaison polypeptidiques préférées.
Booth James E.
Deetz Jeffrey S.
Kelley Brian D.
Potter M. Daniel
Yu Jinan
Dyax Corp.
Smart & Biggar
LandOfFree
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