Binding molecules for the treatment of myeloid cell...

Details Binding molecules for the treatment of myeloid cell... Binding molecules for the treatment of myeloid cell...

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2526284

The present invention provides a human C-type lectin, binding molecules that specifically bind to the human C-type lectin, nucleic acid molecules encoding the binding molecules or the human C-type lectin, compositions comprising the binding molecules or the human C-type lectin and methods of identifying or producing the binding molecules. The human C-type lectin is specifically expressed on myeloid cells and binding molecules capable of specifically binding to the human C-type lectin can be used in the diagnosis, prevention and/or treatment of neoplastic disorders and diseases.

La présente invention concerne une lectine de type C humaine, des molécules de liaison qui se lient spécifiquement à la lectine de type C humaine, des molécules d'acide nucléique codant pour les molécules de liaison ou la lectine de type C humaine, des compositions comprenant les molécules de liaison ou la lectine de type C humaine, ainsi que des procédés pour identifier ou produire les molécules de liaison. La lectine de type C humaine s'exprime de façon spécifique sur des cellules myéloïdes et des molécules de liaison capables de se lier spécifiquement à la lectine de type C humaine, peuvent être utilisées pour le diagnostic, la prévention et/ou le traitement de troubles et de maladies néoplasiques.

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