Binding of complement factor h to c-reactive protein

Details Binding of complement factor h to c-reactive protein Binding of complement factor h to c-reactive protein

G - Physics

01

N

G01N 33/53 (2006.01)

Patent

CA 2648411

The invention relates to a correlation between serum complement Factor H levels and binding to C-reactive protein (CRP) and risk of developing age-related macular degeneration. The invention provides methods for screening a subject to assess risk of developing AMD. The invention also provides methods for screening for agents useful to treat AMD.

L'invention porte sur la corrélation entre les taux du facteur H complémentaire du sérum et la liaison à la protéine C réactive (CRP) et le risque de développement d'une dégénérescence maculaire liée à l'âge. Cette invention porte notamment sur des méthodes de dépistage chez un sujet permettant d'évaluer le risque de développement d'une dégénérescence maculaire liée à l'âge. L'invention porte également sur des méthodes de criblage d'agents utiles pour traiter la dégénérescence maculaire liée à l'âge.

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