Binding partners for inhibitors of cyclin-dependent kinases...

Details Binding partners for inhibitors of cyclin-dependent kinases... Binding partners for inhibitors of cyclin-dependent kinases...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2255143

The present application relates to a protein which inhibits the cellular protein p27 and thereby relieves the inhibition of the proliferation of the cell which is brought about by p27, mutants thereof, some of which possess a dominant interfering character, the corresponding nucleic acids which encode the protein and the use of proteins and nucleic acids for the prophylaxis and therapy of diseases. The application furthermore discloses nucleic acid constructs for the gene therapy of diseases, which constructs comprise the abovementioned nucleic acids.

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