Binding polypeptides for b lymphocyte stimulator protein (blys)

Details Binding polypeptides for b lymphocyte stimulator protein (blys) Binding polypeptides for b lymphocyte stimulator protein (blys)

C - Chemistry, Metallurgy

07

K

C07K 7/00 (2006.01) C07K 1/04 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2418006

Binding polypeptides comprising specific amino acid sequences are disclosed that bind B Lymphocyte Stimulator (BLyS) protein or BlyS-like polypeptides. The binding polypeptides can be used in methods of the invention for detecting or isolating BlyS protein or BlyS-like polypeptides in solutions or mixtures, such as blood, tissue samples, or conditioned media.

L'invention concerne des polypeptides de liaison qui comprennent des séquences aminoacides spécifiques qui se fixent à la protéine stimulatrice des lymphocytes B (BLyS) ou à des polypeptides apparentés à BlyS. Ces polypeptides de liaison peuvent être utilisés dans des méthodes de l'invention pour détecter ou isoler une protéine BlyS ou des polypeptides apparentés à BlyS dans des solutions ou mélanges, tels que du sang, des prélèvements tissulaires, ou des milieux conditionnés.

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