C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 17/00 (2006.01) C07K 14/245 (2006.01) C12M 1/34 (2006.01) C12Q 1/00 (2006.01) G01N 31/22 (2006.01) G01N 33/543 (2006.01)
Patent
CA 2472108
The invention is directed to compositions of mutated binding proteins containing reporter groups, analyte biosensor devices derived from and their use of analyte biosensors both in vitroand in vivo. The binding proteins are covalently bound to a fluorescence dye so that the concentration of an analyte (e.g., glucose) in a given sample is proportional to the fluorescence signal on a scale (Figure 1).
La présente invention concerne des compositions de protéines de liaison mutées contenant des groupes rapporteurs, des dispositifs de biocapteurs d'analytes qui en sont dérivés, et leur utilisation en tant que biocapteurs tant in vitro que in vivo.
Amiss Terry J.
Nycz Colleen M.
Pitner J. Bruce
Sherman Douglas B.
Wright David J.
Becton Dickinson And Company
Gowling Lafleur Henderson Llp
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