Binned micro-vessel density methods and apparatus

Details Binned micro-vessel density methods and apparatus Binned micro-vessel density methods and apparatus

G - Physics

06

T

G06T 7/00 (2006.01)

Patent

CA 2692270

In one aspect, a method of obtaining micro-vessel density (MVD) measurements from an image of biological vasculature containing a plurality of vessels is provided. The method comprises acts of analyzing a region of interest of the image for each of a plurality of bins, each of the plurality of bins associated with a predetermined range of vessel sizes, the act of analyzing the region of interest including determining which of the plurality of bins that portions of any vessel subject matter identified in the region of interest belong based on a size associated with the respective portions of the vessel subject matter, and associating each portion of the vessel subject matter with the corresponding one of the plurality of bins to which the portion belongs, and computing at least one measurement for each of the plurality of bins, the at least one measurement related to the MVD of the portions of vessel subject matter associated with the respective bin.

La présente invention concerne, selon l'un de ses modes de réalisation, un procédé permettant d'obtenir des mesures de la densité de micro-vaisseaux (MDV) à partir d'une image de vasculature biologique renfermant une pluralité de vaisseaux. Le procédé consiste à : analyser une zone d'intérêt de l'image pour chaque pluralité de fichiers, chacune de ces pluralités étant associée à une plage prédéterminée de tailles de vaisseaux; analyser la région d'intérêt et déterminer laquelle de ces pluralités de fichiers possède des parties de vaisseaux identifiés dans la zone d'intérêt sur la base d'une taille associée aux parties respectives des vaisseaux; associer chaque partie des vaisseaux à la pluralité de fichiers correspondante à laquelle elle appartient; et calculer au moins une mesure portant sur la MDV des parties des vaisseaux associées au fichier respectif.

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