Bio-artificial materials with tuneable properties

Details Bio-artificial materials with tuneable properties Bio-artificial materials with tuneable properties

A - Human Necessities

61

L

A61L 27/24 (2006.01) A61L 27/38 (2006.01) A61L 27/52 (2006.01)

Patent

CA 2630919

This invention relates to methods for preparing biomaterials by applying multiple cycles of tensile loading to compacted collagen gels in order to fuse the collagen fibrils together within the compacted gels. This produces a biomaterial with improved material properties. Biomaterials produced by such methods may be useful, for example, as tissue equivalent implants, in the repair and/or replacement of damaged tissue in an individual.

La présente invention a pour objet des méthodes pour préparer des biomatériaux par application de plusieurs cycles de charge de traction afin de compacter des gels de collagène afin de fusionner des fibrilles de collagène dans les gels rendus compacts. Ceci produit un biomatériau ayant des propriétés matérielles améliorées. Les biomatériaux produits par de telles méthodes peuvent être utilisés, par exemple, comme implants équivalents à du tissu, dans le remplacement et/ou la réparation de tissu endommagé chez un individu.

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