C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12P 19/34 (2006.01) G01N 33/533 (2006.01) G01N 33/543 (2006.01) G01N 33/559 (2006.01)
Patent
CA 2335377
The present invention relates to a bio-molecular microchip and manufacturing process thereof. More particularly, the present invention is directed to a bio--molecular microchip manufactured by preparing polyacrylamide gel which contains glycidyl moiety and immobilizing bio-molecule which contains amine group such as nucleotide or polypeptide on polyacrylamide gel through covalent bond formed by epoxy ring-opening reaction between glycidyl moiety of polyacrylamide gel and the amine group contained in said bio-molecule.
La présente invention a trait à une micropuce biomoléculaire et au procédé de fabrication de celle-ci. Plus particulièrement, la présente invention concerne une micropuce biomoléculaire fabriquée en préparant un gel de polyacrylamide comportant un groupement glycidyle, et en immobilisant une biomolécule comptant un groupement amine, comme un nucléotide ou un polypeptide, sur le gel de polyacrylamide, cela grâce à une liaison covalente formée par réaction d'ouverture de cycle époxy entre le groupement glycidyle du gel de polyacrylamide et le groupement amine contenu dans la biomolécule en question.
Ko Han-Ii
Park Han-Oh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Bioneer Corporation
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