Bioactive agent release coating

Details Bioactive agent release coating Bioactive agent release coating

A - Human Necessities

61

L

A61L 29/16 (2006.01) A61K 47/32 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 29/08 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2320259

A coating composition for use in coating medical devices to improve their ability to release bioactive agents in vivo. The coating composition is particularly adapted for use with devices that undergo significant flexion and/or expansion in the course of their delivery and/or use, such as stems and catheters. The composition includes the bioactive agent in combination with a mixture of a first polymer component such as poly(butyl methacrylate) and a second polymer component such as poly(ethylene-co-vinyl acetate).

L'invention concerne une composition de revêtement, utile pour enrober des dispositifs médicaux, afin d'améliorer la capacité de ceux-ci à libérer des agents bioactifs in vivo. Cette composition de revêtement est notamment conçue pour être utilisée avec des dispositifs subissant une flexion et/ou une expansion importantes, lors de leur apport et/ou utilisation, tels que des extenseurs et cathéter, et elle comprend un agent bioactif combiné à un mélange d'un premier polymère, tel qu'un poly(butylméthacrylate) et un second polymère tel qu'un poly(éthylène-co-vinylacétate).

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