Bioactive calcium phosphate composite layers...

A - Human Necessities – 61 – L

Patent

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A61L 27/32 (2006.01) A61F 2/28 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2416201

The invention relates to calcium phosphate composite layers which are electrochemically deposited on bone implants. Implants which are coated in such a way are implanted without cement and are characterised by improved growing-in behaviour. Said highly porous composite layers on implants are made of at least two calcium phosphate phases of different solubility. The highly porous structure of said layers facilitates the immobilisation of cells from which new bone tissue can be made. The different solubility of the individual layer components ensures local concentration of calcium and phosphate ions which accelerates the incorporation process and which adapts to said process over the course of time.

L'invention concerne des couches composites de phosphate de calcium bioactives déposées électrochimiquement sur des implants osseux. De tels implants sont implantés sans ciment et se caractérisent par un pouvoir d'ostéointégration amélioré. Lesdites couches composites ultra-poreuses destinées à des implants sont composées d'au moins deux phases de phosphate de calcium de solubilités différentes. La structure ultra-poreuse de ces couches permet de simplifier l'immobilisation de cellules à partir desquelles le tissu osseux peut se régénérer. Les solubilités différentes des composantes de couches individuelles permettent d'obtenir la concentration locale d'ions calcium et d'ions phosphate accélérant le processus de guérison et s'adaptant au processus dans le temps.

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