Bioactive coating compositions for medical devices

Details Bioactive coating compositions for medical devices Bioactive coating compositions for medical devices

A - Human Necessities

61

L

A61L 31/10 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2563253

A coating composition and related method for use in applying a bioactive agent to a surface in a manner that will permit the bioactive agent to be released from the coating in vivo. The composition is particularly well suited for coating the surface of implantable medical device, such as a stent or catheter, in order to permit the device to release bioactive agent to the surrounding tissue over time. The composition includes a plurality of compatible polymers having different properties that can permit them to be combined together to provide an optimal combination of such properties as durability, biocompatibility, and release kinetics.

La présente invention concerne une composition de revêtement et un procédé afférent à utiliser dans l'application d'un agent bioactif sur une surface d'une manière qui permettra à l'agent bioactif d'être libéré du revêtement in vivo. La composition est particulièrement bien adaptée pour enduire la surface de dispositifs médicaux implantables, tels que des stents ou des cathéters, afin de permettre au dispositif de libérer un agent bioactif dans le tissu environnant au cours du temps. La composition comprend une pluralité de polymères compatibles ayant différentes propriétés leur permettant d'être combinés ensemble pour fournir une combinaison optimale de propriétés telles que la durabilité, la biocompatibilité et la cinétique de libération.

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