Bioactive nanocomposites and methods for their use

A - Human Necessities – 61 – L

Patent

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A61L 27/40 (2006.01) A61L 27/46 (2006.01)

Patent

CA 2438965

Orthopedic compositions are provided that include a homogeneous mixture of a biocompatible polymer and a bioactive particulate ceramic wherein the ceramic has an average particle size of not more than 500 nm are provided. The compositions may be used to form bone cement or various spinal implants, including spinal spacers, interbody fusion cages, bone plates and bone screws. Methods for stabilizing a spine, for correcting a bone defect, and for promoting fusion of adjacent vertebare are also provided.

L'invention concerne des compositions orthopédiques qui comportent un mélange homogène d'un polymère biocompatible et d'une céramique particulaire bioactive, ladite céramique ayant une granulométrie moyenne n'excédant pas 500 nm. La composition peut servir à former du ciment osseux ou divers implants rachidiens, y compris des écarteurs vertébraux, des dispositifs de fusion osseuse, des plaques vissées et des vis d'os. L'invention concerne également des procédés destinés à stabiliser un dos, à corriger un défaut osseux et à favoriser la fusion de vertèbres adjacentes.

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