Bioactive substance k93-0711 1-1 and 1-2, and process for...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) C07D 491/04 (2006.01) C07D 491/048 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2195291

Solution : Bioactive substance K93-0711 I-1 and I-2 producing microorganism belonging to genus Streptomyces is cultured in a medium ; bioactive substance K93-0711 I-1 and 1-2 is accumulated in the mediuim ; and bioactive substance K93-0711 I-1 and I-2 is isolated therefrom. Effect : Effective for treatment of IL-6 involving diseases such as cancer cachexia, multiple myeloma and rheumatoid arthritis.

olution : un microorganisme du genre Streptomyces produisant les substances biologiquement actives K93-0711 I-1et I-2 est cultivé en milieu de culture; les substances biologiquement actives K93-0711 I-1 et 1-2 s'accumulent dans le milieu et en sont isolées. Effet : efficace pour le traitement des troubles mettant en jeu l'IL-6 comme la cachexie du cancéreux, le myélome multiple et l'arthrite rhumatoïde.

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