Bioactive surface layer for bone implants

Details Bioactive surface layer for bone implants Bioactive surface layer for bone implants

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61L 27/32 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2276015

A bioactive surface layer with 0.01 µm to 5 mm thickness is suitable for a metallic bone implant. The surface layer has the following composition: (A) calcium compounds (CaX) consisting of crystalline calcium phosphate (CaP), calcium apatites (CaAp) and/or calcium carbonate (CaCO3), in a proportion expressed by the following equation: 100 % (CaX) = .SIGMA.[x % (CaP) + y % (CaAp) + z % (CaCO3)], in which x + y + z = 100, 0x100; 0y100; 0z100, and in the form of particles of 20 nm to 4 mm; and (b) amorphous or crystalline metal oxide (MeO). The ratio between CaX and MeO in the surface layer can be preferably varied as a result of the specific coating process. The thickness of the surface layer lies between 0.01 µm and 5 mm and the CaX particles are 20 nm to 4 mm large.

Cette couche superficielle bioactive d'une épaisseur de 0,01 µm à 5 mm est conçue pour un implant osseux métallique. La couche superficielle a la composition suivante: (A) des composés de calcium (CaX) constitués de phosphate de calcium cristallin (CaP), d'apatites de calcium (CaAp) et/ou de carbonate de calcium (CaCO¿3?), dans la proportion définie par la formule suivante: 100 % (CaX) = .SIGMA.[x % (CaP) + y % (CaAp) + z % (CaCO¿3?)], dans laquelle x + y + z = 100, 0?x?100; 0?y?100; 0?z?100, sous forme de particules ayant des dimensions comprises entre 20 nm et 4 mm; et (b) un oxyde métallique cristallin ou amorphe (MeO). Le rapport entre CaX et MeO dans la couche superficielle peut de préférence varier en fonction du procédé spécifique de revêtement. L'épaisseur de la couche superficielle se situe entre 0,01 µm et 5 mm et les dimensions des particules de CaX entre 20 nm et 4 mm.

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