Bioavailable capsule compositions of amorphous...

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A61K 31/4245 (2006.01) A61K 47/10 (2006.01)

Patent

CA 2758847

Pharmaceutical capsule compositions containing the active compound (2R)-2-[[(4- chlorophenyl)sulfonyl][[2-fluo-ro-4-(1,2,4-oxadiazol-3-yl) phenyl]methyl]amino]-5,5,5- trifluoropentanamide, and polyethylene glycol (PEG), Vitamin E polyethylene glycol succinate, polyvinylpryrrolidone (PVP) or copovidone (PVP- Polyvinyl acetate), with or without citric acid, are provided.

L'invention porte sur des compositions de gélules pharmaceutiques contenant le principe actif (2R)-2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phényl]méthyl]amino]-5,5,5-trifluoropentanamide et du polyéthylène glycol (PEG), du polyéthylène glycol succinate de vitamine E, du polyvinylpyrrolidone (PVP) ou du copovidone (PVP-poly(acétate de vinyle)), avec ou sans acide citrique.

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