A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/00 (2006.01)
Patent
CA 2758709
Amorphous solid dispersion compositions containing (2R)-2-[[(4- chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]- 5,5,5-trifluoropentanamide and either polyvinylpyrrolidone-vinyl acetate or hydroxypropyl-- methylcellulose acetate succinate are provided for tabletting.
La présente invention concerne des compositions sous forme de dispersions solides amorphes contenant (2R)-2-[[(4-chlorophényl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phényl]méthyl]amino]-5,5,5-trifluoropentanamide et soit le copolymère polyvinylpyrrolidone-acétate de vinyle, soit de l'acétate-succinate d'hydroxypropylméthylcellulose pour la fabrication de comprimés.
Haddadin Raja M.
Hartley Ruiling F.
Qian Feng
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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