Biocatalysts with amine acylase activity

Details Biocatalysts with amine acylase activity Biocatalysts with amine acylase activity

C - Chemistry, Metallurgy

12

N

C12N 9/80 (2006.01) C12N 1/20 (2006.01) C12P 13/00 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2252616

The invention belongs to the field of biotechnology. It concerns a biocatalyst, i.e. a dead or living microorganism or a polypeptide, preferably in isolated form, which exhibits acylase enzymatic activity without lipase- or esterase-activity. The biocatalyst is capable of stereoselectively hydrolysing a racemic acylamide which has an aliphatic acyl residue and which is not a derivative of a natural amino acid.

L'invention appartient au domaine de la biotechnologie et elle concerne un biocatalyseur, c'est à dire un micro-organisme mort ou vivant, ou un polypeptide, de préférence sous forme isolée, qui démontre une activité enzymatique acylase, sans activité lipase ou estérase. Ce biocatalyseur peut hydrolyser de manière stéréosélective un acylamide racémique, lequel possède un reste acyle aliphatique et n'est pas un dérivé d'un acide aminé naturel.

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