C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 1/00 (2006.01) B01J 19/00 (2006.01) C07K 1/04 (2006.01) G01N 33/566 (2006.01) G01N 33/94 (2006.01) G01N 35/00 (2006.01)
Patent
CA 2169456
This invention encompasses methods for producing a library of modified starting compounds by use of biocatalytic reactions on a staring compound and identifying the modified starting compound with the optimum desired activity. The invention encompasses starting compounds and modified compounds that are free in solution. The method is useful in producing modified pharmaceutical compounds with desired specific activity.
Procédés de production d'une bibliothèque de composés de départ modifiés selon lesquels on utilise des réactions biocatalytiques sur un composé de départ, puis on identifie le composé de départ modifié ayant l'activité désirée optimale. Cette invention concerne des composés de départ et des composés modifiés qui sont libres en solution. Ce procédé est utile pour produire des composés pharmaceutiques modifiés possédant l'activité spécifique désirée.
Clark Douglas S.
Dordick Jonathan S.
Fox J. Wesley
Albany Molecular Research Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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