Biochemical markers of the human endometrium

Details Biochemical markers of the human endometrium Biochemical markers of the human endometrium

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) C07H 21/00 (2006.01) C07K 16/18 (2006.01) C12N 5/16 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2265470

Assay methods are provided for detection or quantitation of any of several proteins which are specifically produced in the endometrium in association with hyperplasia, adenocarcinoma or the proliferative phase of the endometrium. The relevant proteins have been identified by 2D gel electrophoresis with subsequent sequence identification by mass spectroscopic finger printing of tryptic digests.

L'invention porte sur des procédés relatifs à des essais de détection ou de quantification de l'une des protéines spécifiquement produites par l'endomètre en association avec l'hyperplasie, l'adénocarcinome, ou les phases proliférantes de l'endomètre. Les protéines concernées ont été identifiées par électrophorèse sur gel 2D avec identification subséquente par prise au spectre de masse des empreintes des produits de digestion de la trypsine.

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