Biochemically balanced peritoneal dialysis solutions

A - Human Necessities – 61 – M

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A61M 1/28 (2006.01) A61K 9/08 (2006.01) A61K 31/19 (2006.01) A61K 31/7004 (2006.01) A61K 33/00 (2006.01) A61K 33/06 (2006.01) A61K 33/14 (2006.01)

Patent

CA 2169451

A peritoneal dialysis solution that is biochemically balanced to correct metabolic acidosis associated with chronic renal failure in a more physiological manner. The peritoneal dialysis solution has a physiological pH, e.g., pH of 7.0 to 7.4, and contains bicarbonate at a that is found in normal blood. Additionally the solution contains carbon dioxide at a partial pressure that is similar to partial pressure of carbon dioxide found in normal blood. The peritoneal dialysis solution also contains a weak acid with a pKa of less than 5Ø

Solution de dialyse péritonéale équilibrée sur le plan biochimique afin de corriger d'une manière plus physiologique l'acidose métabolique associée à une insuffisance rénale chronique. Cette solution possède un pH physiologique, par exemple un pH compris entre 7,0 et 7,4, et elle contient du bicarbonate dont la concentration est celle trouvée dans un sang normal. En outre, cette solution contient du dioxyde de carbone à une pression partielle semblable à la pression partielle du dioxyde de carbone trouvé dans un sang normal. La solution de dialyse péritonéale comprend également un acide faible possédant un pKa inférieur à 5,0.

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