Biocompatibility of solid surfaces

Details Biocompatibility of solid surfaces Biocompatibility of solid surfaces

C - Chemistry, Metallurgy

07

K

C07K 17/06 (2006.01) A61L 27/00 (2006.01) A61L 29/00 (2006.01) A61L 31/00 (2006.01) A61L 33/00 (2006.01)

Patent

CA 2112644

ABSTRACT An improved spacer material for improving the biocompatibility of a biomaterial and a method for making it in which a polyalkylimine is covalently attached to an aminated substrate and combined with a crosslinking agent which is at least difunctional in aldehyde groups. The polyalkylimine can be, for example, polyethyleneimine and the crosslinking agent can be, for example, glutaraldehyde. Preferably, the crosslinking agent is applied in dilute solution and at a pH suitable to accomplish light crosslinking of the polyalkylimine and also provide aldehyde linkages at the interface between the biomolecule and the spacer.

Affiliated with

Also associated with

Rating

Biocompatibility of solid surfaces does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biocompatibility of solid surfaces, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biocompatibility of solid surfaces will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1847266