Biocompatible and biodegradable porous matrix in particular...

Details Biocompatible and biodegradable porous matrix in particular... Biocompatible and biodegradable porous matrix in particular...

C - Chemistry, Metallurgy

08

J

C08J 9/08 (2006.01) A61L 27/18 (2006.01) A61L 27/60 (2006.01)

Patent

CA 2625604

The invention mainly concerns a biocompatible and biodegradable porous matrix, characterized in that it is made of a three-block sequenced copolymer of formula (I): X G Y (I), wherein: G is a non-hydroxylated hydrophilic linear block, and X and Y represent respectively a hydrophobic linear polyester block. The invention further concerns the use of said matrix for coating tissue reconstruction after loss of substance or bioactive dressings.

La présente invention vise à titre principal une matrice poreuse biocompatible et biodégradable, caractérisée en ce qu'elle est formée d'un copolymère séquence tribloc répondant à la formule (I) : X - G - Y (I) dans laquelle : G est un bloc linéaire hydrophile, non hydroxylé, et X et Y représentent respectivement un bloc polyester linéaire hydrophobe. Selon une variante priviligée de l~invention, le copolymère consiste en PLA50-PEG-PLA50. Elle vise en outre l'utilisation de ladite matrice dans le domaine de la reconstruction des tissus de revêtement après perte de substance ou à celui des pansements bioactifs.

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