C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 303/16 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2706914
Fumagillin analog polymer conjugates, methods of making fumagillin analog polymer conjugates, compositions comprising a polymer conjugate of a fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a polymer conjugate of a fumagillin analog, are described. Also described are novel fumagillin analogs, methods of making fumagillin analogs, compositions comprising at least one fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a fumagillin analog.
La présente invention concerne des conjugués polymériques d'analogues de fumagilline, des procédés de fabrication de conjugués polymériques d'analogues de fumagilline, des compositions contenant un conjugué polymérique d'un analogue de fumagilline, et des procédés permettant de traiter le cancer, ou de traiter des maladies angiogéniques. Lesdits procédés consistent à administrer à un sujet nécessitant le traitement une quantité efficace d'un conjugué polymérique d'un analogue de fumagilline. L'invention concerne également de nouveaux analogues de fumagilline, des procédés de fabrication d'analogues de fumagilline, des compositions contenant au moins un analogue de fumagilline, et des procédés permettant de traiter le cancer, ou de traiter des maladies angiogéniques, lesdits procédés consistant à administrer à un sujet nécessitant le traitement une quantité efficace d'un analogue de fumagilline.
Akullian Laura C.
Hammond Charles E.
Kane John J.
Petter Russell C.
Stevenson Cheri A.
Mbm Intellectual Property Law Llp
Mersana Therapeutics Inc.
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