Biocompatible, biodegradable polyurethane materials with...

C - Chemistry – Metallurgy – 08 – G

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C08G 18/66 (2006.01) A61L 26/00 (2006.01) C08G 18/32 (2006.01) C08G 18/42 (2006.01) C08G 18/67 (2006.01)

Patent

CA 2574933

The biocompatible, biodegradable materials in the solid and/or liquid form are based on segmented linear polyurethanes and/or segmented crosslinked polyurethanes based on A) one or more biocompatible polyols susceptible to hydrolytic and/or enzymatic degradation having a molecular weight of 100 to 20,000 dalton and a number of active hydroxyl groups per molecule (functionality) of at least two or higher; B) one or more diisocyanates and/or triisocyanates; and C) one or more low molecular weight chain extenders having a molecular weight of 18 to 1000 dalton and the functionality of at least two or higher.

L'invention porte sur des matériaux biocompatibles et biodégradables solides et/ou liquides à base de polyuréthanes linéaires segmentés et/ou de polyuréthanes réticulés comportant: (A) un ou plusieurs polyols biocompatibles susceptibles de dégradation hydrolytique et/ou enzymatique d'un poids moléculaire de 100 à 20 000 dalton et dont le nombre de groupes hydroxyle par molécule (fonctionnalité) est au moins de 2; (B) un ou plusieurs diisocyanates et/ou triisocyanates; et (C) un ou plusieurs extenseurs de chaîne de faible poids moléculaire compris entre 18 et 1000 dalton et présentant une fonctionnalité d'au moins 2.

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