A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/114, 204/91.
A61K 35/14 (2006.01) A61M 1/36 (2006.01)
Patent
CA 1264031
ABSTRACT OF THE DISCLOSURE The present invention discloses the effect of ultra- violet (UV) radiation on platelet concentrates collected in a plastics container, particularly in a polypropylene bag. Samples irradiated at 310 nm for 30 minutes at a dose of 774 J/M2 show no loss of platelet function as determined by ADP, collagen, or ristocetin-induced aggregation. Lymphocytes isolated from irradiated units are unable to act as responders or stimulators in a mixed lymphocyte reaction. The invention provides a device and a method of UV irradiation of platelet concentrates resulting in transfusible cell suspension unable to evoke immunological response while retaining normal platelet function.
498979
Kahn Richard Allen
Rodey Glenn Eugene
American National Red Cross
Borden Ladner Gervais Llp
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