Biocompatible microporous polymeric materials and methods of...

A - Human Necessities – 61 – L

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18/28, 167/326,

A61L 27/00 (2006.01) A61F 2/06 (2006.01) A61F 13/00 (2006.01) A61L 15/26 (2006.01) A61L 15/42 (2006.01) A61L 27/18 (2006.01) B29C 47/00 (2006.01) C08J 9/28 (2006.01) A61F 2/00 (2006.01) A61F 13/15 (2006.01)

Patent

CA 1322834

63884-29 Abstract of the Disclosure A microporous biocomatible material is formed by preparing a segmented polyether urethane urea solution con- taining 25% = 1.5% solids dissolved in a solvent. The solution has sufficient viscosity to be preshaped and formed into the desired thickness of the finished article, then immediately immersed into a precipitation bath in which the solvent in the solution is miscible for a time interval sufficient to cause the solution to set up into an opaque elastomeric article. The article is immediately removed from the bath, any excess 801- vent extracted and the article is then dried at a temperature on the order of 35°C. to 70°C. followed by heat treating by annealing for approximately sixty minutes at a temperature at 100°C. to 130°C. The void volume of the membrane solution is controlled to within the 50% to 80% range and the pore size from ca <0.1 to several mms. as well as the shape of the pores and solid structures between them, thereby enabling close con- trol over the characteristics and structure of the material as well as other variations in structural characteristics and por- osity across the thickness of the material according to its intended application and use.

520830

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