Biocompatible polymer blends and uses thereof

Details Biocompatible polymer blends and uses thereof Biocompatible polymer blends and uses thereof

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2466998

The present invention relates to a novel series of polymers which have been prepared by blending hydrophobic biocompatible, biodegradable polymers or copolymers, such as poly(lactide-co-glycolide), and a biocompatible, amphipathic copolymer having a water absorption ratio of about 2 or less. A process for the preparation of the novel polymer blends and sustained release compositions comprising the novel polymer blends are also part of the invention described herein. Further the sustained release compositions can be used to deliver a biologically active with a desirable release profile and in a sustained fashion to a patient in need thereof.

L'invention concerne une nouvelle série de polymères préparés par mélange de polymères ou de copolymères biodégradables, biocompatibles hydrophobes, tels que le poly(lactide-co-glycolide), et un copolymère biocompatible, amphipathique ayant un taux d'absorption d'eau d'environ 2 ou moins. L'invention concerne également un procédé de préparation desdits mélanges de polymères et de compositions à libération retardée comprenant les nouveaux mélanges de polymères. En outre, les compositions à libération retardée peuvent être utilisées pour délivrer à un patient, en cas de besoin, un produit biologiquement actif ayant un profil de libération désirable, avec action retardée.

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