Biocompatible polymeric delivery systems for sustained...

A - Human Necessities – 61 – F

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A61F 2/02 (2006.01) A61F 13/02 (2006.01)

Patent

CA 2557524

The present invention relates to biocompatible polymeric delivery systems for controlled or sustained release of quinazolinone derivatives, including the compound halofuginone. In particular the invention relates to a polymeric delivery system comprising biocompatible polymeric beads having a two-phase core and shell structure, or polymeric films, beads or complexes that provide local sustained release of the pharmacological agent.

La présente invention se rapporte à des systèmes de distribution polymères biocompatibles, destinés à la libération contrôlée ou prolongée de dérivés de la quinazolinone, notamment du composé halofuginone. En particulier, l'invention a trait à un système de distribution polymère qui contient des billes polymères biocompatibles possédant une structure à deux phases noyau-enveloppe, ou des films, billes ou complexes polymères qui assurent la libération prolongée de l'agent pharmacologique.

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