Biocompatible polyurea-urethane hydrated polymers

C - Chemistry – Metallurgy – 08 – G

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400/107, 402/125

C08G 18/48 (2006.01)

Patent

CA 1335316

A class of hydrophilic prepolymers and hydrated polymer gels is disclosed which are characterized by their transparency, biocompatibility and resistance to nonspecific protein adsorption. At least 75%, preferably at least 90%, of the prepolymers are isocyanate-capped oxyethylene-based diols or polyols having molecular weight of about 7000-30,000. Essentially all of the hydroxyl groups of the diols or polyols are capped with polyisocyanate prior to formation of the hydrated polymer.

562042

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