Biodegradable

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/58 (2006.01) A61K 6/033 (2006.01) A61K 6/087 (2006.01) A61L 24/00 (2006.01) A61L 24/04 (2006.01) A61L 27/26 (2006.01)

Patent

CA 2516728

The present invention provides a method for making biodegradable and bioresorbable biomaterials that are also characterized by its malleability. Any desired shape can be obtained from this material, resulting from the specific composition of this invention. Therefore, the biomaterial of the present invention is very well suited to be used as in preparation of implants for dental applications, or as in the case of difficult accessible sites such as bone cavities. Composition of the biomaterial comprises an hydrophobic biopolymer, a compound having both hydrophilic and hydrophobic properties, bone regenerative entity that help in the bone regeneration. In addition, these biomaterials can be used as vehicle for the release of biologically active entities or drugs, such as growth factors or analgesics for example.

La présente invention concerne un procédé de fabrication de biomatériaux biodégradables et biorésorbables qui sont également caractérisés par leur malléabilité. La composition spécifique de l'invention permet d'obtenir n'importe quelle forme du matériau précité. C'est pourquoi le biomatériau de l'invention est particulièrement bien adapté à la préparation d'implants destinés à des applications dentaires, ou dans le cas de sites difficilement accessibles tels que les cavités osseuses. Dans la composition du biomatériau de l'invention entrent un biopolymère hydrophobe, un composé possédant des propriétés à la fois hydrophiles et hydrophobes, et une entité de régénération osseuse qui facilite la régénération osseuse. En outre, ces biomatériaux peuvent être utilisés comme véhicules destinés à la libération d'entités ou médicaments à activité biologique, tels que des facteurs de croissance ou des analgésiques, par exemple.

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