Biodegradable block copolymeric compositions for drug delivery

Details Biodegradable block copolymeric compositions for drug delivery Biodegradable block copolymeric compositions for drug delivery

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61F 2/00 (2006.01) A61K 31/765 (2006.01) A61K 31/77 (2006.01) C08L 71/02 (2006.01)

Patent

CA 2489771

An improved drug delivery composition and method of us is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. The composition can be administered as is or after being be dissolved or rapidly reconstituted in an aqueous vehicle to afford a homogeneous solution or uniform colloidal systems.

L'invention concerne une composition et un procédé d'administration de médicaments. La composition comprend un ou plusieurs excipients de médicaments copolymères blocs biodégradables et un agent permettant la reconstitution et améliorant celle-ci, qui comprend du polyéthylèneglycol (PEG), un dérivé de PEG ou un mélange de PEG et d'un dérivé de PEG. La composition peut être administrée telle quelle ou après avoir été dissoute ou reconstituée rapidement dans un milieu aqueux pour permettre la formation d'une solution homogène ou de systèmes colloïdaux uniformes.

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