C - Chemistry – Metallurgy – 04 – B
Patent
C - Chemistry, Metallurgy
04
B
C04B 35/622 (2006.01) A61K 9/70 (2006.01) A61L 31/14 (2006.01) C03B 37/01 (2006.01) C03B 37/04 (2006.01) C04B 35/14 (2006.01)
Patent
CA 2359699
The present invention relates to a method for preparing controllably biodegradable silica fibres. The method com-prises spinning the fibres from a silica sol, the viscosity of the sol being controlled. Further, the present invention relates to control-lably biodegradable silica fibres prepared according to the invention and methods for controlling the biodegradability of the fibres. The invention also relates to controllably biodegradable fibres as sustained and/or controlled release delivery devices for biologically active agents, and to pharmaceutical preparations comprising such devices.
La présente invention concerne un procédé de préparation de fibres de silice biodégradables de manière contrôlée. Le procédé consiste à filer des fibres issues d'un sol siliceux dont la viscosité est contrôlée. Cette invention concerne également des fibres de silice biodégradables de manière contrôlée préparées selon l'invention et des procédés de contrôle de la biodégradabilité des fibres; ainsi que des fibres biodégradables de manière contrôlée qui sont utiles en tant que dispositifs d'apport à libération lente et/ou contrôlée destinés à des agents biologiquement actifs et des compositions pharmaceutiques contenant ces mêmes dispositifs.
Ahola Manja
Jokinen Mika
Kortesuo Pirjo
Peltola Timo
Veittola Sinikka
Bioxid Oy
Delsitech Oy
Robic
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