Biodegradable foam

A - Human Necessities – 61 – L

Patent

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Details

A61L 15/28 (2006.01) A61L 15/42 (2006.01) A61L 27/20 (2006.01) A61L 27/56 (2006.01) A61L 31/14 (2006.01)

Patent

CA 2643083

The invention relates to a method for forming a dried absorbent foam having an open pore network and pores by preparing an aqueous dispersion comprising an enzymatically biodegradable biopolymer and a foaming agent and optionally one or more of gel-forming ions, a plasticizer, a crosslinking agent and a pH modifier, forming, preparing or mixing a foam from the aqueous dispersion and drying the foam to form a dried foam containing open pores. Gelled composites made from the foams are also provided. The invention is particularly useful in providing foams and composites for use in biomedical applications and as an anti-adhesive in tissue regeneration and wound management.

L'invention concerne un procédé servant à former une mousse absorbante séchée ayant un réseau de pores ouverts et des pores en préparant une dispersion aqueuse comprenant un biopolymère biodégradable par des enzymes et un agent moussant et éventuellement un ou plusieurs ions formant un gel, un plastifiant, un agent de réticulation et un modificateur du pH, en formant, préparant ou mélangeant une mousse à partir de la dispersion aqueuse et en séchant la mousse pour former une mousse séchée contenant des pores ouverts. L'invention concerne également des composites gélifiés formés à partir des mousses. L'invention est particulièrement utile pour fournir des mousses et des composites destinés à être utilisés dans des applications biomédicales et en tant qu'antiadhésif dans la régénération de tissus et la gestion de plaies.

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