Biodegradable ionic matrix of variable internal polarity...

Details Biodegradable ionic matrix of variable internal polarity... Biodegradable ionic matrix of variable internal polarity...

A - Human Necessities

61

K

A61K 9/51 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2266642

The invention concerns a particulate biodegradable matrix comprising: a biodegradable and hydrophilic core with a base of a carbohydrate or polyol or polyamine matrix, cross-linked and derived in the mass by variable amounts of ionic groups; a hydrophilic polymer layer, associated to the central core by chemical, for example ionic, interaction; surface molecules or polymers grafted on the external polymer layer by covalent bonds.

Matrice particulaire biodégradable comportant: un noyau hydrophile et biodégradable à base d'une matrice d'hydrate de carbone ou de polyols ou de polyamines, réticulée et dérivée dans la masse par des taux variables de groupements ioniques; une couche polymérique hydrophile, associée au noyau central par des interactions chimiques, par exemple ioniques; des molécules ou des polymères de surface greffés sur la couche polymérique externe par des liaisons covalentes.

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