A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/22 (2006.01) A61K 47/16 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2585664
A method and a composition for delivery of a biomaterial to an animal cell or a tissue, the composition includes (a) a biomaterial; (b) a biodegradable cross-linker portion having a hydrolyzable bond, wherein the biodegradable cross-linker portion is covalently bound to the biomaterial; and (c) a substrate, wherein the substrate is covalently bound to the biodegradable cross-linker portion, provided that the biodegradable cross-linker is adapted to hydrolyze by breaking the hydrolyzable bond and thereby release and deliver the biomaterial. A method of making the composition is also provided. A process of delivery of a biomaterial to an animal cell or a tissue is also provided.
L'invention concerne un procédé et une composition pour l'administration d'un biomatériau à une cellule ou à un tissu animal, ladite composition comprenant : (a) un biomatériau ; (b) une portion de réticulation biodégradable présentant une liaison hydrolysable, ladite portion de réticulation biodégradable étant liée par covalence au biomatériau ; et (c) un substrat, lequel est lié par covalence à la portion de réticulation biodégradable, étant entendu que le réticulant biodégradable est adapté pour s'hydrolyser par rupture de la liaison hydrolysable, de manière à libérer et à administrer le biomatériau. L'invention concerne en outre un procédé de fabrication de ladite composition. L'invention concerne également un procédé d'administration d'un biomatériau à une cellule ou à un tissu animal.
Alferiev Ivan
Fishbein Ilia
Levy Robert J.
Blake Cassels & Graydon Llp
The Children's Hospital Of Philadelphia
LandOfFree
Biodegradable linkers for molecular therapies does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Biodegradable linkers for molecular therapies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biodegradable linkers for molecular therapies will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2085750