Biodegradable poly(amino acid)s derivatized amino acid...

C - Chemistry – Metallurgy – 08 – G

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C08G 69/10 (2006.01) C02F 5/12 (2006.01) C08G 69/42 (2006.01) C08G 69/48 (2006.01) C08G 73/02 (2006.01) C08G 73/10 (2006.01)

Patent

CA 2205717

New and improved polyamino acid polymers and derivatized polyamino acid polymers are provided. Relatively high molecular weight poly(succinimides) are prepared by solid phase polymerization of aspartic acid or glutamic acid in the presence of a super phosphoric acid catalyst. The poly(succinimides) may be hydrolyzed to provide biodegradable polyaspartic acid or polyglutamic acid homopolymer having weight average molecular weights >= 70,000. Higher molecular weight, water soluble, cross-linked polyamino acid polymers and gels are also provided. In a preferred embodiment, the poly(succinimides) are derivatized in aqueous media to provide storage stable, substantially linear, biodegradable polyamino acid polymers having pendant hydroxyl, ether, hydroxy-alkylaminoalkyl, hydroxyalkoxyalkyl, carboxyl, sulfonoalkyl and/or phosphonoalkyl functionalities. The polymers are useful as chelants in various water treatment applications.

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