Biodegradable polycarbonates and their use as drug carriers

Details Biodegradable polycarbonates and their use as drug carriers Biodegradable polycarbonates and their use as drug carriers

C - Chemistry, Metallurgy

08

G

C08G 63/64 (2006.01) A61K 9/16 (2006.01) A61K 47/34 (2006.01) A61M 37/00 (2006.01) C08G 64/02 (2006.01) C08G 64/42 (2006.01)

Patent

CA 2128621

2128621 9320126 PCTABS00027 A biodegradable and biocompatible polycarbonate comprising (C3-10) alkylene carbonic acid ester units, each alkylene group being a C3-alkylene group having 1 oxy substituent or a (C4-10) alkylene group having 2-8 oxy substituents, each of the oxy substituents occurring individually as a hydroxyl group or as a derivatized hydroxyl group comprising an ester or an ortho ester or an acetal residue. The polycarbonates may be used as matrices for the sustained release of pharmacologically active compounds, e.g. peptides or proteins, in the form of microparticles or implants.

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